Research publications

Chakravarti, A, Thirimane, H, Brown, S, and Calvi, B.R. (2022) Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control. eLife, 11:e61389 doi: 10.7554/eLife.61389

Chakravarti, A, Thirimane, H, and Calvi, B.R. (2020) Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control. BioRxiv doi: https://doi.org/10.1101/2020.07.21.214692

Danny E. Miller, Lily Kahsai, Kasun Buddika, Michael J. Dixon, Bernard Y. Kim, Brian R. Calvi, Nicholas S. Sokol, R. Scott Hawley and Kevin R. Cook (2020) Identification and characterization of breakpoints and mutations on Drosophila melanogaster balancer chromosomes G3: Genes, Genomes, Genetics 10 (11), 4271-4285.

Rotelli, M.D., Bolling, A.M., Killion, A.W., Weinberg, A.J., Dixon, M.J., and Calvi, B.R. (2019) An RNAi screen for genes reguired for growth of Drosophila wing tissue. G3 9(10): 3087-3100.

Rotelli, M.D., Policastro, R., Bolling, A.M., Killion, A.W., Weinberg, A.J., Dixon, M.J., Zentner, G., Lilly, M., Walczak, C., and Calvi, B.R. (2019) A Cyclin A–Myb-MuvB–Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles. PLoS Genet 15: e1008253.

Robin, M., Issa, A.R., Santos, C.C., Napoletano, F., Petitgas, C., Chatelain, G., Ruby, M., Walter, L., Birman, S., Domingos, P.M., Calvi, B.R. and Mollereau, B. (2018) Drosophila p53 integrates the antagonism between autophagy and apoptosis in response to stress. Autophagy, 5:771-784

Lesly, S., Bandura, J.L., Calvi, B.R. (2017) Rapid DNA Synthesis During Early Drosophila Embryogenesis Is Sensitive to Maternal Humpty Dumpty Protein Function. Genetics 207, 935-947.PMC5676233. (featured in Highlight section and one of our micrographs was featured on the Genetics website)

Zhang, C, Montooth, K.L., and Calvi, B.R. (2017) Incompatibility between mitochondrial and nuclear genomes during oogenesis results in ovarian failure and embryonic lethality. Development, 144, 2490-2503 doi:10.1242/dev.151951

Chen, S., Stout, J. R., Dharmaiah, S., Yde, S., Calvi, B.R. and Walczak, C.E. (2016) Transient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability Mol. Biol. Cell, 27:2911-2923

Qi, S., and Calvi, B.R. (2016) Different cell cycle modifications repress apoptosis at different steps independent of developmental signaling in Drosophila. Mol. Biol. Cell, 27:1885-1897

Paranjape, N, and Calvi, B.R. (2016) The histone variant H3.3 is enriched at Drosophila amplicon origins but does not bookmark them for pre-RC assembly or activation. Genes Genomes and Genetics (G3) 6:1-11, 10.1534/g3.116.028068

Liu J, Zimmer K, Rusch DB, Paranjape N, Podicheti R, Tang H, Calvi B.R. (2015). DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila. Nucleic Acids Res. gkv766

Zhang B, Rotelli M, Dixon M, Calvi, B.R. (2015) The function of Drosophila p53 isoforms in apoptosis. Cell Death Differ. doi: 10.1038/cdd.2015.40

Zhang, B., Mehrotra, S., Ng, W. L., and Calvi, B.R. (2014) Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells. PLoS Genetics in press, September.

Calvi BR. (2014) HBO1:JADE1 at the cell cycle chromatin crossroads. Cell Cycle 2014; 13:15, 2322–2322.

Hassel, C., Zhang, B., Dixon, M., and Calvi, B.R. (2014) Induction of endocycles represses apoptosis independent of differentiation and predisposes cells to genome instability. Development 141:112-123.

McConnell, K., Dixon, M., and Calvi, B.R. (2012) The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in Drosophila ovarian follicle cells. Development, 139: 3880-3890. PMD 22951641.

Liu, J., McConnell, K., Dixon, M. and Calvi, B.R. (2011) Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the pre-RC. Mol. Biol. Cell. 23(1): 200-212 PMID:22049023.

Maqbool SB, Mehrotra S, Kolpakas A, Durden C, Zhang B, Zhong H, Calvi BR. (2010) Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells. J Cell Sci. 123: 4095-4106. PMID: 21045111.

Mehrotra, S, Maqbool, SB, Kolpakas A, Murnen K, and Calvi, BR. 2008. Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress. Genes & Development 22:3158-3171.

Drosophila 12 Genome Consortium (2007). Genomics on a phylogeny: Evolution of Genes and Genomes on the Drosophila phylogeny. Nature 450: 203-218.

Calvi, BR, Byrnes, BA, and Kolpakas, AJ. 2007. Conservation of epigenetic regulation, ORC binding, and developmental timing of DNA replication origins in the genus Drosophila. Genetics: 177:1291-1301.

White, AE, Leslie, ME, Calvi, BR, Marzluff, WF, and Duronio,RJ. 2007. Cyclin E/CDK2 regulation of the Drosophila melanogaster histone locus body. Molecular Biology of the Cell: 18(7), 2491-2502.

May, NR, Thomer, M, Murnen, KF, and Calvi, BR. 2005. The origin binding protein Double parked, and its inhibitor Geminin, increase in response to replication stress. Journ. Cell Sci. 118:4207-4217.

Bandura JL, Beall E, Bell M, Silver H, Botchan, M, and Calvi, BR. 2005. humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila. Current Biology 15: 755-759. (Current Biology Cell Press Paper of the Month)

Thomer, M, May, NR, Aggarwal, BD, Kwok, G, and Calvi, BR. 2004. Drosophila double-parked is sufficient for re-replication during development and is regulated by Cyclin E / CDK2. Development 131(19): 4807-4818.

Aggarwal, BD, and Calvi, BR. (2004).Chromatin regulates origin activity in Drosophila follicle cells. Nature 430: 372-376. (Reviewed in Faculty of 1000).

Schwed GM, May NR, Pechersky Y, Calvi BR. (2002). Drosophila MCM6 is required for chorion gene amplification and genomic replication. Mol. Biol. of the Cell 13(2): 607-620.

Calvi BR, Spradling AC. (2001). The nuclear location and chromatin organization of active chorion amplification origins. Chromosoma 110: 159-172.

Calvi BR, Lilly MA, Spradling AC. (1998). Cell cycle control of chorion gene amplification. Genes & Development 12(5): 734-44.

Calvi BR, Gelbart WM (1994). The basis for germline specificity of the hobo transposable element in Drosophila melanogaster. EMBO Journal 13(7): 1636-44.

Smith D, Wohlgemuth J, Calvi BR, Franklin I, Gelbart WM. (1993). hobo enhancer trapping mutagenesis in Drosophila reveals an insertion specificity different from P elements. Genetics 135(4): 1063-76.

Calvi BR, Hong TJ, Findley SD, Gelbart WM. (1991). Evidence for a common evolutionary origin of inverted repeat transposons in Drosophila and plants: hobo, Activator, and Tam3. Cell 66(3): 465-71.

Reviews, commentaries, and book chapters

Alliance of Genome Resources (2020). Alliance of Genome Resources Portal: unified model organism research platform. Nucleic Acids Res 48: D650-D658. (NAR breakthrough of the year).

Alliance of Genome Resources C. (2019). The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases. Genetics 213: 1189-1196.

Thurmond, J., Goodman, J.L., Strelets, J.B., Atrill, H., Gramates, L.S., Marygold, S.J., Matthews, B. B., Millburn G., Antonazzo, G., Trovisco, V., Kaufman, T.C., Calvi, B.R.¹, and the FlyBase Consortium (2019) Flybase 2.0: The next Generation. Nucleic Acids Research 47:D759 ID (1: Communicating author)

Douglas G. Howe, Judith A. Blake, Yvonne M. Bradford, Carol J. Bult, Brian Calvi, Stacia R. Engel, James A. Kadin, Thom Kaufman, Ranjana Kishore, Stanley J. F. Laulederkind, Suzanna E. Lewis, Sierra A. T. Moxon, Joel E. Richardson, Cynthia Smith(2018) Model organism data evolving in support of translational medicine. Nature Lab Animal47:277-289.

Calvi, B.R. (2013) Making Big Cells: One size does not fit all. Proceedings of the National Academy of Sciences, 110 (24) 9621-9622 (invited commentary).

B. R. Calvi Developmental Gene Amplification. In: DNA Replication and Human Disease. Cold Spring Harbor Laboratory Press. Melvin DePamphilis (ed.) (2006), pp 233-255.

B. R. Calvi and Mary A. Lilly: Brdu labeling and nuclear flow sorting of the Drosophila ovary. Drosophila Cytogenetics Protocols. Daryl Henderson (eds.). Humana Press, USA, 2002.

Jennifer L. Bandura and B. R. Calvi: Duplication of the genome in normal and cancer cell cycles. Cancer Biology and Therapy 1(8), 2002.

B. R. Calvi and Allan C. Spradling: Chorion gene amplification in Drosophila: a model for metazoan origins of DNA replication and S phase control. "Genetic Approaches to Eukaryotic Replication and Repair" Methods in Enzymology. Paul Fisher (eds.). Vol. 18: 407-417, 1999.